Two-dimensional high-throughput on-cell screening of immunoglobulins against broad antigen repertoires
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP510088
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资源简介:
Identification of potent antibodies in human serum is difficult due to limited B cells targeting specific antigens. Our efficient method enriches high-affinity antibodies against pathogens, even without knowledge on immunogens structure. Our two-step screening approach allows the selection selects high-affinity therapeutic human antibodies, in particular against SARS-CoV-2 spike protein, within weeks.
创建时间:
2024-05-29



