PSN1 Polysome and INK128

NIAID Data Ecosystem2026-03-10 收录

mRNA翻译调控

药物辐射效应

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48098 数据链接链接失效反馈

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资源简介：

Polysome-bound mRNA was analyzed to determine the effects of INK128 and radiation on mRNA translation 4 samples were analyzed with 3 biological replicates

创建时间：

2018-08-23

Co-transcriptional pseudouridylation of mRNAs by the H/ACA complex controls translational efficiency [ChIP-seq]. Co-transcriptional pseudouridylation of mRNAs by the H/ACA complex controls translational efficiency [ChIP-seq]

mRNA翻译调控

假尿苷修饰机制

Post-transcriptional modifications of mRNA have emerged as novel regulators of gene expression. Pseudouridylation is the most abundant and widespread type of RNA modification in living organisms; howe

NIAID Data Ecosystem40

The LARP1 La-Module recognizes both ends of TOP mRNAs

RNA结合蛋白

mRNA翻译调控

La-Related Protein 1 (LARP1) is an RNA-binding protein that regulates the stability and translation of mRNAs encoding the translation machinery, including ribosomal proteins and translation factors. T

DataCite Commons2021-05-09 更新10

CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function

mRNA翻译调控

突触功能分子机制

RNA–binding proteins have emerged as causal agents of complex neurological diseases. Mice deficient for neuronal RNA–binding protein CELF4 have a complex neurological disorder with epilepsy as a promi

Figshare2016-01-19 更新00

GCN2 suppresses TOP mRNA translation via LARP1

mRNA翻译调控

营养应激响应

La-related protein 1 (LARP1) has been identified as a key translational inhibitor of terminal oligopyrimidine tract (TOP) mRNAs downstream of the nutrient sensing protein kinase complex, mTORC1. LARP1

NIAID Data Ecosystem30

Absence of SMARCB1 in rhabdoid tumor cells increases sensitivity to translation inhibition and alters translation efficiency of specific mRNAsn. Absence of SMARCB1 in rhabdoid tumor cells increases sensitivity to translation inhibition and alters translation efficiency of specific mRNAsn

癌症分子机制

mRNA翻译调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem00