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Alpha-fluoro acid and alpha-fluoro amide analogs of acetyl-coa as inhibitors of of citrate synthase: effect of pka matching on binding affinity and hydrogen bond length

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Alpha-fluoro acid and alpha-fluoro amide analogs of acetyl-coa as inhibitors of of citrate synthase: effect of pka matching on binding affinity and hydrogen bond length Descriptor: ALPHA-FLUORO-AMIDOCARBOXYMETHYLDETHIA COENZYME A COMPLEX, CITRATE SYNTHASE, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1995-08-04 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: alpha-Fluoro acid and alpha-fluoro amide analogs of acetyl-CoA as inhibitors of citrate synthase: effect of pKa matching on binding affinity and hydrogen bond length. Biochemistry, 34, 1995

乙酰辅酶A(acetyl-CoA)的α-氟代酸与α-氟代酰胺类似物作为柠檬酸合酶(citrate synthase)抑制剂:pKa匹配对结合亲和力与氢键长度的影响 描述符:α-氟代酰胺基羧甲基脱硫辅酶A复合物、柠檬酸合酶、草酰乙酸离子 作者:Usher, K.C.、Remington, S.J. 提交日期:1995-08-04 发布日期:1995-10-15 最后修改日期:2024-02-07 实验方法:X射线衍射(1.7 Å) 引用文献:乙酰辅酶A的α-氟代酸与α-氟代酰胺类似物作为柠檬酸合酶抑制剂:pKa匹配对结合亲和力与氢键长度的影响. 《生物化学(Biochemistry)》,34卷,1995年
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1995-08-04
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