Genes differentially expressed between Leishmania infantum wild type and LinPIWI(−/−) axenic amastigotes as assessed by DNA microarray analysis.

aGene functions are based on Gene Ontology (GO) annotation. The main categories are shown here.bStage-specific gene expression of the modulated transcripts in the L. infantum LinPIWI(−/−) mutant is based on the data by [38], [44].cThere is some discrepancy between the intracellular and axenic amastigote microarray data. These genes seem to be more expressed in promastigotes when comparing L. infantum intracellular amastigotes to promastigotes.dA probe recognizing LinJ.14.0710, LinJ.14.0720¸ LinJ.14.0730, LinJ.14.0740 and LinJ.14.0760 showed that theses genes were more expressed in the amastigote stage. Another probe recognizing LinJ.14.0710 and LinJ.14.0720 showed that theses genes were more expressed in the promastigote stage.*Genes encoding proteins with one to several transmembrane domains.