CellDeathPred: a deep learning framework for ferroptosis and apoptosis prediction based on cell painting

Data Description:

Two cell death modalities are considered in this study: apoptosis and ferroptosis. The treatments and their cell death types used in these experiments are shown in Figure 1 in the paper. In total we have seven apoptosis and seven ferroptosis inducers. They target specific cell organelles and components. Besides, active treatments there are negative controls DMSO and untreated wells.

Every image has a resolution of 1360 x 1024. These four channels were imaged in the experiments. For every well multiple images (fields) are taken typically ten fields.

Three plates with four different settings were imaged. 20x non-confocal (very fast [1.5h]), 20x confocal (fast [2.5h]), 40x non-confocal (slow [5h]), 40x confocal (very slow [8h]). All for one time point 28h (incubation time).