Data for: Hysterectomy and sexual (dys)function: An analysis of sexual dysfunction after hysterectomy and a search for predictive factors

Abstract Objectives Research about sexual function after hysterectomy is inconclusive. Possible predictive factors for sexual (dys)function are yet to be identified. The aim of this study is to assess the effect of hysterectomy on sexual function in women 3 and 12 months after hysterectomy for benign indications. Furthermore hypothesized predictive factors will be evaluated. Methods A prospective multicentre cohort study with follow-up at 3 and 12 months after hysterectomy was performed. To assess sexual function a short-form FSFI was used, a score ≤ 19 means sexual dysfunction). Linear mixed model repeated measure analysis was used to assess changes in sexual function in women who were sexually active at all three measure points (N=260). Linear mixed model analyses were also used for the predictor analyses. Results The FSFI score increased from 20.94 at baseline to 23.81 at 12 months post hysterectomy. The number of women experiencing sexual dysfunction was 86 (33.1%). Women without preoperative sexual dysfunction had a significantly higher FSFI score 4.5 (95% CI 3.5-5.6) one year after the operation than women indicating sexual dysfunction before surgery. Women who were living alone had a significantly higher FSFI score of 2.31 (0.7-4.0) when compared to women who were married or living together. Conclusion FSFI score increases significantly after hysterectomy, which indicates a better sexual function after the operation. Sexual dysfunction before hysterectomy (FSFI score ≤ 19) and being married or living together are predictive factors for a lower FSFI score post hysterectomy.

摘要 目的 目前关于子宫切除术后女性性功能的研究结论尚不统一，性功能（障碍）的潜在预测因子仍有待明确。本研究旨在评估因良性指征接受子宫切除术的女性，在术后3个月及12个月时的性功能变化情况，并对预先假设的预测因子进行分析验证。方法 本研究为前瞻性多中心队列研究，对受试者在子宫切除术后3个月及12个月进行随访。采用简化版女性性功能指数（Female Sexual Function Index, FSFI）评估性功能，得分≤19提示存在性功能障碍。针对三个时间点均有性活动的260名受试者，采用线性混合模型重复测量分析评估其性功能变化；预测因子分析亦采用线性混合模型进行。结果 受试者的FSFI得分从基线时的20.94提升至术后12个月的23.81。共有86名（33.1%）受试者存在性功能障碍。术前无性功能障碍的女性，术后1年的FSFI得分较术前存在性功能障碍的女性显著高出4.5分（95%置信区间：3.5~5.6）。独居女性的FSFI得分较已婚或与伴侣同居的女性显著高出2.31分（95%置信区间：0.7~4.0）。结论 子宫切除术后女性的FSFI得分显著升高，提示术后性功能有所改善。术前存在性功能障碍（FSFI得分≤19）以及已婚/与伴侣同居，是术后FSFI得分较低的预测因子。