Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine

ChEBI2011-08-01 更新2026-07-21 收录

疟原虫药物响应

抗疟药物作用机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31109 数据链接链接失效反馈

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资源简介：

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine

创建时间：

2011-08-01

Real-Time Imaging of the Intracellular Glutathione Redox Potential in the Malaria Parasite Plasmodium falciparum

疟原虫机制研究

抗疟药物作用机制

In the malaria parasite Plasmodium falciparum, the cellular redox potential influences signaling events, antioxidant defense, and mechanisms of drug action and resistance. Until now, the real-time det

NIAID Data Ecosystem80

Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors. Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors

抗疟药物作用机制

寄生虫代谢重编程

Spiroindolone and pyrazoleamide antimalarial compounds target Plasmodium falciparum P-type ATPase (PfATP4) and induce disruption of intra-cellular Na+ homeostasis. Recently, a PfATP4 mutation was disc

NIAID Data Ecosystem40

Calcium dysregulation is the critical initiator in high dose chloroquine-induced programmed cell death of Plasmodium falciparum

抗疟药物作用机制

疟原虫细胞死亡机制

Understanding the mechanism of action of novel antimalarial drugs is a key goal in eradicating malaria. Previously we have explored a possible alternative cell death mechanism that is elicited by micr

NIAID Data Ecosystem20

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites. [RNA]

疟原虫机制研究

抗疟药物作用机制

The goal of our study is to characterize the global transcriptional resposne of P.falciparum to DNA damageing agents. Alongside, we stidied the epigenetic regulation of DNA damage resposne in parasit

NIAID Data Ecosystem50

Additional file 1: of Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study

疟原虫药物响应

转录组学分析

Microarray data analysis from DHA treatment. Limma results from 1, 2, and 3Â h 500 nM DHA treatments in P. falciparum K1 trophozoites. (XLS 2986Â kb)

Figshare2016-12-15 更新20