The advent of feeding based RNAi in Caenorhabditis elegans led to an era of gene discovery in aging research. Hundreds of gerogenes were discovered, and many are evolutionarily conserved, raising the
Here we apply tailocins to barcoded random transposon-insertion (RB-TnSeq) mutant libraries of 4 groundwater Pseudomonads (FW300-N2C3, FW300-N2E2, FW300-N2E3, GW456-L13) to identify genetic determinan
We performed a platform for the unbiased identification of functional serine (S), threonine (T), and tyrosine (Y) at a genome-wide scale, which is highly relevant with phosphorylation. Using CRISPR-de
In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
Changes in gene expression in a pancreatic cancer cell line and a chemoresistant line on treating with the drug CM03 Overall design: Changes at 6 h and 24 h were evaluated with RNA-seq with respect to
