Abatacept Restores Dysregulated Transcriptomic and Proteomic Profile in Disorders of CTLA-4 Insufficiency

The source data accompanying the manuscript includes the raw data files from both the NanoString gene expression analysis and the SomaLogic plasma proteomics analysis. These datasets serve as the foundational resources for the computational and statistical analyses conducted within the study, providing transparency and reproducibility. For the NanoString gene expression analysis, the data are formatted to be compatible with the nSolver Analysis Software, which is specifically designed for processing and analyzing NanoString data. This software enables users to perform quality control, normalization, and differential expression analysis with precision. Experimental data resulting from the SomaLogic assay is provided by the manufacturer in a proprietary text-based format called ADAT. This data can be analyzed via the Life Sciences Portal. The portal offers user-friendly software enabling users to perform quality control, normalization, and differential expression analysis using appropriate statistical methods.