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The global transcriptomic profile in the spermidine-stressed E. coli

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE186526
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To achieve extreme spermidine stress we used DspeG E. coli strain. We identified the pathways that are altered under spermidine stress. Among many changes spermidine altered the iron-sulfur cluster metabolism and redox balance in the cells. Therefore, we have shown that superoxide quencher, NAC and ascorbate mitigates spermidine stress. Overall our data explains the importaance of tight spermidine homeostasisin the cell. Organism : Escherichia coli , Agilent custom E.coli Gene Expression 8x15k Array (AMADID: 068043) designed by Genotypic Technology Private
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2022-03-02
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