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Anti-virulence compound 187R inhibits P. aeruginosa T3SS without affecting microbiota

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP245653
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Antivirulence therapy is considered as a promising alternative antimicrobial therapy since it targets virulence factors rather survival. As a result, anti-virulence therapy should present less selective pressure and have less impact to the host-associated microbiota. However, the systematic evaluation of the impact of antivirulence compounds on the host microbiota was limited. In this project, impact of antivirulence compound on the host-associated microbial community was also tested using Arabidopsis thaliana phyllosphere as a model.
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2022-12-09
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