The involvement of the human prefrontal cortex in the emergence of visual awareness

Exploring the neural mechanisms of awareness is a fundamental task of cognitive neuroscience. There is an ongoing dispute regarding the role of the prefrontal cortex (PFC) in the emergence of awareness, which is partially raised by the confound between report- and awareness-related activity. To address this problem, we designed a visual awareness task that can minimize report-related motor confounding. Our results show that saccadic latency is significantly shorter in the aware trials than in the unaware trials. Local field potential (LFP) data from 6 patients consistently show early (200-300 ms) awareness-related activity in the PFC, including event-related potential and high-gamma activity. Moreover, the awareness state can be reliably decoded by the neural activity in the PFC since the early stage, and the neural pattern is dynamically changed rather than being stable during the representation of awareness. Furthermore, the enhancement of dynamic functional connectivity, through the ..., This dataset was collected from six adult patients with drug-resistant epilepsy (6 males, 32.33±4.75 years old, mean±SEM) and 10 healthy subjects (4 males, 6 females, age 27.80 ± 3.92, mean ± SEM) participated in this study. All subjects had normal or corrected-to-normal vision. Eye position data was collected from all the participants, obtaining by an infrared eye tracker (Jsmz EM2000C, Beijing Jasmine Science & Technology, Co. Ltd), sampling at 1 kHz. Electrophysiological signals (LFPs) and brain images (magenetic resonance imaging (MRI) and computed tomography (CT) scans) were obtained from 6 patients. Stereotaxic EEG depth electrodes (SINOVATION MEDICAL TECHNOLOGY CO., LTD. Ltd., Beijing, China) containing 8 to 20 sites were implanted in patients in the Department of Neurosurgery, PLA General Hospital. Each site was 0.8 mm in diameter and 2 mm in length, with 1.5 mm spacing between adjacent sites. A few electrodes were segmented, and the distance between the two segments was 10 ..., , # Dataset for the eLife article entitled 'The involvement of the human prefrontal cortex in the emergence of visual awareness' The dataset contains raw eye position data and sEEG data obtained within the study \"The involvement of the human prefrontal cortex in the emergence of visual awareness\". The dataset was produced to assess the involvement of the man prefrontal cortex in the emergence of visual awareness. ## Description of the data and file structure In this dataset, the healthy control data includes eye position data, while the patient data includes the eye position data, the seeg data and the brain image data. Details for the dataset: There are two folders in the Dataset, including the 'Healthy Control Data' and 'Patients Data' folder. Healthy Control Data: There are ten folders named 'xx_VisualAwareData' and each contains the behavioral data of each healthy control. The '.mat' files contain the raw behavioral data that required to analyze behavioral performance in each...探索意识的神经机制是认知神经科学的一项基础研究任务。目前关于前额叶皮层（prefrontal cortex, PFC）在意识产生过程中的作用仍存在持续争议，该争议部分源于报告相关神经活动与意识相关神经活动之间的混淆。为解决这一问题，我们设计了可最小化报告相关运动混淆的视觉意识任务。研究结果显示，有意识试次中的眼跳潜伏期显著短于无意识试次。来自6名患者的局部场电位（local field potential, LFP）数据一致显示，前额叶皮层存在早期（200~300 ms）的意识相关活动，包括事件相关电位与高伽马活动。此外，早在早期阶段，前额叶皮层的神经活动即可可靠解码意识状态，且在意识表征过程中，神经模式呈动态变化而非稳定状态。进一步而言，动态功能连接的增强通过…… 本数据集采集自6名成人耐药性癫痫患者（6名男性，年龄32.33±4.75岁，均值±标准误）与10名健康受试者（4名男性、6名女性，年龄27.80±3.92岁，均值±标准误）。所有受试者视力正常或经矫正后达到正常水平。所有参与者均通过红外眼动追踪仪（Jsmz EM2000C, Beijing Jasmine Science & Technology, Co. Ltd）采集眼位数据，采样率为1 kHz。6名患者同时采集了电生理信号（局部场电位）以及脑成像数据（磁共振成像（MRI）与计算机断层扫描（CT））。中国人民解放军总医院神经外科为患者植入了带有8~20个记录位点的立体定向脑电图深度电极（SINOVATION MEDICAL TECHNOLOGY CO., LTD., Beijing, China），每个位点直径0.8 mm、长度2 mm，相邻位点间距1.5 mm。部分电极存在分段结构，两段间距离为10…… # 对应eLife期刊论文《人类前额叶皮层参与视觉意识的产生》的数据集 本数据集包含本研究中采集的原始眼位数据与立体定向脑电图（stereotaxic electroencephalogram, sEEG）数据，旨在评估人类前额叶皮层在视觉意识产生过程中的作用。 ## 数据与文件结构说明 本数据集包含两个文件夹，分别为「健康对照组数据」与「患者组数据」。 健康对照组数据：包含10个命名为「xx_VisualAwareData」的文件夹，每个文件夹对应一名健康受试者的行为学数据。其中的「.mat」格式文件包含用于分析每名受试者行为表现的原始行为数据……