Anaplastic ependymoma and H3K27M-mutant diffuse midline glioma were analyzed and compared by scRNA-seq. Tumor samples were collected from patients with clinical anaplastic ependymoma (EPN) and one H3K

NIAID Data Ecosystem30

Clinical characteristics of all tissue samples from glioma patients.

胶质瘤分子特征

神经肿瘤学

Clinical characteristics of all tissue samples from glioma patients.

Figshare2016-09-28 更新10

EZH2 inhibition in glioblastoma stem cells is associated with increased expression of neuronal genes and the neuronal developmental regulators ZIC2, ZNF423 and MAFB

神经肿瘤学

表观遗传调控

Here we use two GBM stem cell lines, representing the classical/pro-neural and mesenchymal GBM subtypes, to investigate the effects of three different EZH2 inhibitors on GBM stem cell survival and gen

NIAID Data Ecosystem30

Single-cell RNAseq of control and COMT-KO glioma tumors in mice.. Single-cell RNAseq of control and COMT-KO glioma tumors in mice.

神经肿瘤学

单细胞转录组学

Next-generation sequencing (NGS)-derived transcriptomic profiling was carried out to compare the transcriptomic changes mediated by COMT knockout CT2A glioblastoma tumors using an orthotopic mouse mod

NIAID Data Ecosystem10

Chronic stress accelerates pancreatic cancer tumorigenesis by promoting the acinar-induced increase in Slc6a2 in nerves

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