PLCG1

ENCODES a protein that exhibits calcium-dependent phospholipase C activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); insulin receptor binding (ortholog); INVOLVED IN positive regulation of epithelial cell migration; calcium ion transport (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); adult T-cell leukemia/lymphoma (ortholog); Alzheimer's disease (ortholog); FOUND IN clathrin-coated vesicle (ortholog); glutamatergic synapse (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; 1-stearoyl-2-arachidonoylphosphatidic acid; dihexadecanoyl phosphatidic acid

编码一种表现出钙依赖性磷脂酶C活性（同源物）、鸟苷酸核苷酸交换因子活性（同源物）、胰岛素受体结合（同源物）的蛋白质；参与上皮细胞迁移的正向调控；钙离子转运（同源物）；在宫内胚胎发育（同源物）中发挥作用；参与E-钙粘蛋白信号通路；ephrin-ephrin受体双向信号轴；表皮生长因子/神经生长因子信号通路；与急性心肌梗死（同源物）、成人T细胞白血病/淋巴瘤（同源物）、阿尔茨海默病（同源物）相关；存在于网格蛋白包被的囊泡（同源物）、谷氨酸能突触（同源物）、质膜（同源物）；与1,2-二硬脂酰基-sn-甘油-3-磷酸胆碱、1-硬脂酰-2-花生四烯酰磷酸脂、二硬脂酰磷酸脂相互作用。