In silico recognition of a prognostic signature in basal-like breast cancer patients
收藏NIAID Data Ecosystem2026-03-14 收录
官方服务:
资源简介:
Scientific research for publishing the article
应用场景:
创建时间:
2023-02-20
相关数据集
Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer
Dickkopf 3 (DKK3) has been associated with tumor suppression of various tumor entities including breast cancer. However, the functional impact of DKK3 on the tumorigenesis of distinct molecular breast
NIAID Data Ecosystem100
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting). Homo sapiens
Differentiation events contribute to cellular heterogeneity within tumors and influence disease progression and response to therapy. Here we dissect the mechanisms controlling intratumoral heterogenei
NIAID Data Ecosystem90
Luminal Stem Cell Determinant SOX9 Controls Lineage Plasticity and Progression in Basal-Like Breast Cancer (Sox9-KO)
Lineage plasticity plays an important role in the development of basal-like breast cancer (BLBC), an aggressive cancer subtype. Although studies suggest BLBC is likely to originate from luminal progen
NIAID Data Ecosystem60
Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas
Basal breast cancers, an aggressive breast cancer subtype that has poor treatment options, are thought to arise from luminal mammary epithelial cells that undergo basal-like plasticity through poorly
NIAID Data Ecosystem90
ATF3-induced mammary tumors exhibit molecular features of human basal-like breast cancer
Transcriptional profiling of mammary tumors that occurs in parous, BK5.ATF3 mice, compared to adjacent normal mammary tissue Two-condition experiment, BK5.ATF3-induced mammary tumors v. adjacent norma
NIAID Data Ecosystem60



