Tracking the genetic evolution of daptomycin resistance in Staphylococcus aureus using an in vitro bioreactor model
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA446060
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资源简介：
We describe a novel approach to studying the accumulation of genetic mutations that lead to enhanced DAP-R in N315, a highly DAP-S strain of S. aureus. We employed a continuous culture model using a bioreactor which, eliminates the conditions of nutrient limitation and allows bacterial replication to occur unhindered except for antibiotic exposure.
创建时间：
2018-03-28
