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Multicomponent Approach in the Synthesis of 2,2,6-Trisubstituted Morpholine Derivatives

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https://figshare.com/articles/dataset/Multicomponent_Approach_in_the_Synthesis_of_2_2_6_Trisubstituted_Morpholine_Derivatives/2476726
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资源简介:
An efficient synthesis of 2,2,6-trisubstituted morpholine is described which involves a multicomponent process by simply mixing epichlorohydrin, N-bromosuccinimide, nosyl amide, and an olefin. The products contain chloride handles which are suitable for further modification.
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2016-02-20
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