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FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

ChEBI2013-06-27 更新2026-07-21 收录

细胞表观遗传学

FGF信号通路调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42923 数据链接链接失效反馈

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FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

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创建时间：

2013-06-27

细胞表观遗传学

ATAC-Seq染色质开放性分析

Next Generation Sequencing data of ATAC-Seq library of Thp1-mono, Thp1-macro, and Thp1-M.tb We constructed ATAC-Seq library of 3 samples (Thp1-mono, Thp1-macro, and Thp1-M.tb), and for each sample we

NIAID Data Ecosystem60

ATACseq of AXIN2-/+ hepatocytes and AXIN2+ intestinal stem cells (ISCs) and LGR4/5KO hepatocytes

细胞表观遗传学

WNT信号调控

Previous studies have shown low expression of metabolic genes in ISCs and low expression of cell cycle genes in hepatocytes (HEP). Here, we perform ATACseq to exam differential usage of WNT signaling

NIAID Data Ecosystem50

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of Ã-cell function [scATAC-seq]

昼夜节律代谢

细胞表观遗传学

Circadian rhythm disruption (CD) is associated with dysregulation of glucose homeostasis and Type 2 diabetes mellitus (T2DM). While the link between CD and T2DM remains unclear, there is accumulating

NIAID Data Ecosystem30

Type I IFNs and TNF Cooperatively Reprogram Epigenomic Landscape of Human Macrophages to Promote Inflammatory Activation

细胞表观遗传学

炎症免疫调节

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem60

Mint-ChIP-seq from naive thymus-derived CD8-positive, alpha-beta T cell (ENCSR652WFO)

组蛋白修饰ChIP-seq

细胞表观遗传学

H3K36me3 Mint-ChIP-seq on human naive thymus-derived CD8-positive, alpha-beta T cell For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Page

NIAID Data Ecosystem40

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

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