Phosphorylation of L1 by p90rsk

p90rsk associates with the internalized L1 in the endosomes and phosphorylates it at Ser1152. This phosphorylation may regulate the interactions of L1 and intracellular signaling cascades or cytoskeletal elements involved in neurite outgrowth on specific substrates.

p90rsk与内化于早期内体中的L1蛋白相结合，并在Ser1152位点上对其进行磷酸化。此次磷酸化可能调节L1蛋白与细胞内信号级联反应或参与特定底物上神经突生长的细胞骨架元素之间的相互作用。