Meta regression results in which several variables were analyzed trough simple linear regressions.

Coef. (B) is the regression coefficient of each regression, representing the slope of each model. Significant observations (p<0.05) are highlighted in bold. D.f. = degrees of freedom; HDRS = Hamilton Depression Rating Scale; rTMS = repetitive transcranial magnetic stimulation; AD = antidepressant drug; MADRS = Montgomery-Asberg Depression Rating Scale; MDD = Major Depressive Disorder; Y/N = yes or no. (*) There are no escitalopram studies that enrolled patients with refractory MDD. (**) All escitalopram studies except one assessed post-treatment scores at week 8.