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Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid Descriptor: 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase Authors: Gouge, J, Delarue, M. Deposit date: 2013-01-13 Release date: 2013-09-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013

与抑制剂6-[4-(3-氟苯甲酰基)-1H-吡咯-2-基]-2-羟基-4-氧代己-2,5-二烯酸结合的末端脱氧核苷酸转移酶(Terminal deoxynucleotidyl Transferase, TdT)核心 描述符:6-[4-(3-氟苯甲酰基)-1H-吡咯-2-基]-2-羟基-4-氧代己-2,5-二烯酸、DNA核苷酸转移酶 作者:Gouge J、Delarue M 沉积日期:2013-01-13 发布日期:2013-09-04 最后修改日期:2023-09-20 实验方法:X射线衍射(2.6 Å) 引用文献:《末端脱氧核苷酸转移酶的新型核苷酸竞争性非核苷类抑制剂:发现、表征及其与靶标复合物的晶体结构》,J.Med.Chem.,56卷,2013年
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2013-01-13
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