The association between sub-clinical atherosclerosis measured from the carotid artery and the genetic risk score formed from 24 risk variants previously associated with coronary artery disease.

Adjustments: Model 1 – unadjusted; Model 2 – age, sex and Body Mass Index; Model 3a – age, sex, body mass index, apoliprotein A, apolipoprotein B, systolic blood pressure and waist circumference; Model 3b – age, sex, body mass index, blood glucose, waist circumference and diastolic blood pressure.
*Beta for a change of one standard deviation in the risk score.
**For an increase of one risk allele in the GRS24SNP/CAD.
***The 6-year incidence of carotid atherosclerosis is defined as the occurrence of substantial CIMT (age-, sex- and BMI- adjusted CIMT- value over 90% percentile) or plaque in 2007 in subjects who did not have substantial CIMT or plaque in 2001.
Abbreviations: S.E., Standard Error; OR, Odds Ratio; CI, Confidence interval.