Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA in space group P3221
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Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA in space group P3221 Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, DNA/RNA (5'-D(P*AP*GP*C)-R(P*(IU))-D(P*CP*GP*GP*C)-R(P*(IU))-3'), ... Authors: Chen, S.F, Wang, Y.R, Chan, N.L. Deposit date: 2018-04-18 Release date: 2018-08-08 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.873 Å) Cite: Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate. Nat Commun, 9, 2018
空间群P3221下人类拓扑异构酶IIβ(human topoisomerase II beta)与含5-碘尿嘧啶脱氧核糖核酸(5-iodouridine-containing-DNA)结合的晶体结构
结构组成描述:脱氧核糖核酸(DNA,5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3')、DNA拓扑异构酶2-β(DNA topoisomerase 2-beta)、DNA/RNA杂合链(5'-D(P*AP*GP*C)-R(P*(IU))-D(P*CP*GP*GP*C)-R(P*(IU))-3')等
作者:Chen S.F.、Wang Y.R.、Chan N.L.
提交日期:2018-04-18
发布日期:2018-08-08
最后更新日期:2023-11-22
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率3.873埃(Å)
引用文献:《拓扑异构酶II DNA门控调控DNA通道的结构机制》,《自然-通讯》(*Nat Commun*),第9卷,2018年
创建时间:
2018-04-18



