Ocular sequelae of retinopathy of prematurity in Manaus, Amazonas

Abstract Purpose: To evaluate the structural ocular sequelae of retinopathy of prematurity in children at risk for the disease in Manaus, Amazonas, Brazil. Methods: A prospective, cohort-type, observational study was conducted. Fifty-seven children at risk for this retinopathy, who were born in the public health system facilities, were referred for ophthalmic evaluation at a secondary eye hospital. Inclusion criteria were gestational age ≤ 32 weeks and/or birth weight ≤ 1500 g. Results: Eighteen (31.6%) children were diagnosed with any stage of retinopathy of prematurity during the study period, and four (7.0%) of them needed treatment. Structural ocular sequelae were identified in 3 of 56 children (5.3%), consisting of peripheral retinal detachment with macular dragging in 3 eyes of 3 children and macular involving retinal detachment in 2 eyes of 2 children. Associations between occurrence of retinopathy of prematurity and birth weight, gestational age at birth and days in oxygen were observed (p