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The deubiquitinase OTUD1 attenuates periodontal inflammation by restricting neutrophil protein transport

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP404534
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资源简介:
We report that OTUD1 acts as an immune regulator in periodontitis. OTUD1 inhibits neutrophils migration to inflammatory site via blocking surface protein presentation. Our data reveals that activation of OTUD1 may be a potential strategy for periodontitis treatment. Overall design: Study of gingiva infiltration immune cells from WT or Otud1-/- mice in the context of experimental periodontitis using 10x scRNA-seq technologies.
创建时间:
2024-10-31
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