Data for: Democratizing LYTACs—A Modular Click Chemistry Platform for the Rapid Assembly of Lysosome-Targeting Chimeras

Raw .txt MALDI files organized by date of acquisition.

MALDI analysis script in R.

The data were analyzed using the MALDIquant package in RStudio 2024.12.1 Build 563. ChatGPT-4o (OpenAI) was used to assist in the writing of the analysis script.

Gibb, S.; Strimmer, K. Maldiquant: A Versatile R Package for the Analysis of Mass Spectrometry Data. Bioinformatics 2012, 28 (17), 2270–2271. https://doi.org/10.1093/bioinformatics/bts447.

Also included are data from the in vitro flow cytometry and live-cell analysis experiments as .prism files. For the live-cell analysis dataset, representative videos are included as well.

原始.txt格式的基质辅助激光解吸电离（Matrix-Assisted Laser Desorption/Ionization，MALDI）文件按采集日期整理归档。
配套提供R语言编写的MALDI分析脚本。
本数据集采用RStudio 2024.12.1 Build 563环境中的MALDIquant软件包进行数据分析；分析脚本的编写得到了OpenAI的ChatGPT-4o协助。
Gibb S、Strimmer K. MALDIquant：一款用于质谱数据分析的多功能R软件包[J]. Bioinformatics, 2012, 28(17): 2270-2271. DOI: https://doi.org/10.1093/bioinformatics/bts447.
本数据集还包含以.prism文件格式存储的体外流式细胞术与活细胞分析实验数据；针对活细胞分析数据集，同步提供了代表性实验视频。