Theoretical, Cultural, and Perceptual Correlates of Human Papillomavirus Vaccine Acceptance (HPV-VA) and Vaccine Uptake (HPV-VU) in a Hispanic Community

A survey was administered to a community sample of adults aged 18-65 years residing in El Paso, Texas. Survey questions explored theoretical perceptual, and cultural factors that were hypothesized to be associated with HPV-Vaccine Acceptance (HPV-VA) and HPV-Vaccine Uptake (HPV-VU) among the predominately Hispanic population in this region. The purpose of the current study was to examine theoretical (i.e., the Health Belief Model), perceptual (e.g., trust and recommendations from an HCP), and cultural (e.g., language, household size, familism, and religiosity) influences of HPV-VA and HPV-VU in predominately Hispanic community. We hypothesize that theoretical, perceptual, and cultural factors will be associated with HPV-VA and HPV-VU. Specifically, perceived effectiveness, perceived safety, and perceived severity will be positively associated with HPV-VA and HPV-VU; in contrast, perceived harm will be inversely associated with HPV-VA and HPV-VU. We also predicted that one’s family’s attitudes about vaccines would be positively associated with one’s own attitudes about vaccines. Moreover, we explored the role of trust, HCP recommendations, and culture. This research was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award Number U54MD007592. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

本研究向居住于美国得克萨斯州埃尔帕索市的18-65岁成年社区人群发放了调查问卷。问卷围绕与该地区以西班牙裔为主人群的人乳头瘤病毒（Human Papillomavirus, HPV）疫苗接受度（HPV-Vaccine Acceptance, HPV-VA）及HPV疫苗接种率（HPV-Vaccine Uptake, HPV-VU）相关的假说性理论、感知及文化因素展开设计。本研究旨在探讨理论层面（即健康信念模型（Health Belief Model））、感知层面（如对医疗保健提供者（Health Care Provider, HCP）的信任及来自其的接种建议）与文化层面（如语言、家庭规模、家庭主义（familism）及宗教虔诚度（religiosity））因素对该地区以西班牙裔为主的社区人群HPV-VA与HPV-VU的影响。本研究提出假说：理论、感知与文化因素均与HPV-VA及HPV-VU存在关联。具体而言，感知有效性、感知安全性与感知严重性将与HPV-VA及HPV-VU呈正相关；与之相反，感知危害将与二者呈负相关。此外，本研究还预测个体家庭的疫苗接种态度将与个体自身的疫苗接种态度呈正相关，并进一步探讨了信任、HCP建议及文化因素所发挥的作用。本研究获美国国立卫生研究院（National Institutes of Health, NIH）下属少数族裔健康与健康差异研究所资助，资助编号为U54MD007592。本文内容仅代表作者个人观点，未必代表美国国立卫生研究院的官方立场。