Cancer cells educate natural killer cells to a metastasis-promoting cell state. Cancer cells educate natural killer cells to a metastasis-promoting cell state

Gene expression comparisons revealed that healthy NK cells have an active NK cell molecular phenotype, whereas tumor-exposed (teNK) cells resemble resting NK cells. Receptor–ligand analysis between teNK cells and tumor cells revealed multiple potential targets. Overall design: Gene expression from NK cells from tumor bearing mice, teNK, compared to NK cells from healthy donor mice