Time series gene expression in critically ill patients: PREVAIL study. Time series gene expression in critically ill patients: PREVAIL study

The PREVAIL study was a Phase II/III randomized controlled trial examining the use of lactoferrin to prevent nosocomial infections in critically ill patients undergoing mechanical ventilation. Gene expression data was generated from a consecutive subset of patients at the lead study site. We used the Affymetrix PrimeView array to generate expression data at various time points during the ICU stay. Overall design: Time series gene expression profiling of critically ill patients undergoing mechanical ventilation, who were enroled in the PREVAIL study