Opioid-related death during chronic opioid therapy in men and women.

a Hazard ratios presented for men, with women as reference group
b Adjusted for patient age, history of alcohol abuse or alcohol-related comorbidity, previous SSRI use, previous other antidepressant use, previous benzodiazepine use, previous antipsychotic use, previous use of other CNS depressants, and Charlson score
c Adjusted for median number of distinct non-opioid drugs used in past 6 months
Opioid-related death during chronic opioid therapy in men and women.