Effect of the interaction between the rs9939609 SNP or a proxy (r2>0.8) and PA on BMI, waist circumference, body fat percentage, risk of obesity, and risk of overweight in a random effects meta-analysis of up to 218,166 adults.

All models are adjusted for age and sex. Beta is the increase in trait per minor allele of rs9939609 or a proxy (r2>0.8); betainteraction is the difference in trait per minor allele of rs9939069 comparing physically active individuals to inactive individuals, e.g., a betainteraction of −0.14 kg/m2 for BMI represents a 0.14 kg/m2 attenuation in the BMI-increasing effect of the rs9939609 minor allele in physically active individuals compared to inactive individuals; I2 is the heterogeneity between studies in the meta-analysis; interaction OR is the ratio of ORs (OR[physically active]/OR[inactive]) per minor allele of rs9939609, e.g., an interaction OR of 0.92 for risk of obesity indicates that the obesity-increasing effect of the rs9939609 minor allele in physically active individuals is 0.92 of the effect in inactive individuals.1Values are beta/betainteraction for all rows except risk of obesity and risk of overweight, for which values are OR/interaction OR.NA, no data available for analysis.