Impact of 3-amino-1,2,4-triazole (3-AT)-derived increase in hydrogen peroxide levels on inflammation and metabolism in human adipocytes

Name: Impact of 3-amino-1,2,4-triazole (3-AT)-derived increase in hydrogen peroxide levels on inflammation and metabolism in human adipocytes
Creator: Figshare
Published: 2024-12-16 21:41:49
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DataCite Commons2024-12-16 更新2024-07-25 收录

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https://figshare.com/articles/Impact_of_3-amino-1_2_4-triazole_3-AT_-derived_increase_in_hydrogen_peroxide_levels_on_inflammation_and_metabolism_in_human_adipocytes/1587108/1

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Obesity is a multifactorial disease associated with oxidative stress and chronic inflammation and characterized by an excessive accumulation of fat in adipose tissue. Excessive H<sub>2</sub>O<sub>2 </sub>levels are degraded by catalase, whose activity is decreased in obesity. We investigated the effects of inhibition of catalase activity by 3-amino-1,2,4-triazole (3-AT) on the metabolism and inflammation of human differentiated adipocytes.

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Figshare

创建时间：

2017-07-30