Excel file containing differential gene expression analysis comparing the acoziborole-resistant cell line to wild-type T. brucei as output by DESeq2.

The dataset is divided into 4 worksheets. The first contains DESeq2 output from the AcoR cell line analysis; the second contains HTSeq-count output for each sample used in this study. The final two worksheets contain the comparisons of the DESeq2 output from this study to previously published comparisons of slender BSF vs. stumpy form [13], and slender BSF vs. PCFs [48]. These worksheets also contain columns with calculated distance from an “X = Y” line for each gene, in both comparisons. Hypothetically, if log2 fold change for a gene in the AcoR/WT comparison was equal to that from the other comparisons, the gene would fall on an X = Y line when plotted on a scatter plot. These columns are the calculated deviation from this line for each gene. Positive values indicate a higher log2 fold change in the AcoR/WT dataset, and conversely, negative values indicate a lower log2 fold change in the AcoR/WT dataset, when compared to the aforementioned data. (XLSX)