Structure of the Fab fragment of N62, a protective monoclonal antibody to the nonreducing end of Francisella tularensis O-antigen

Structure of the Fab fragment of N62, a protective monoclonal antibody to the nonreducing end of Francisella tularensis O-antigen Descriptor: ACETATE ION, N62 heavy chain, N62 light chain Authors: Lu, Z, Rynkiewicz, M.J, Yang, C.-Y, Madico, G, Perkins, H.M, Wang, Q, Costello, C.E, Zaia, J, Seaton, B.A, Sharon, J. Deposit date: 2013-05-13 Release date: 2013-07-24 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.59 Å) Cite: The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology, 140, 2013

针对土拉弗朗西斯菌（Francisella tularensis）O抗原非还原端的保护性单克隆抗体N62的Fab片段结构。结构描述组分：乙酸根离子、N62重链、N62轻链。作者：Lu Z、Rynkiewicz MJ、Yang C-Y、Madico G、Perkins HM、Wang Q、Costello CE、Zaia J、Seaton BA、Sharon J。提交日期：2013-05-13；发布日期：2013-07-24；最后修改日期：2024-11-27。实验方法：X射线衍射（分辨率2.59埃）。引用文献：针对土拉弗朗西斯菌（Francisella tularensis）O抗原非还原端的单克隆抗体结合位点主要适配末端糖基，《免疫学（Immunology）》，第140卷，2013年。