Hnrnpu
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ENCODES a protein that exhibits poly(G) binding; promoter-specific chromatin binding; ribonucleoprotein complex binding; INVOLVED IN cellular response to dexamethasone stimulus; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; positive regulation of gene expression; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); colorectal cancer (ortholog); developmental and epileptic encephalopathy 1 (ortholog); FOUND IN ribonucleoprotein complex; catalytic step 2 spliceosome (ortholog); cell surface (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
编码一种表现出多聚(G)结合特性的蛋白质;特异性启动子染色质结合;核糖核蛋白复合物结合;参与细胞对地塞米松刺激的响应;正调控DNA拓扑异构酶(ATP水解)活性;正调控基因表达;参与剪接体途径;与自闭症谱系障碍(同源物)、结直肠癌(同源物)、发育性和癫痫性脑病1(同源物)相关;存在于核糖核蛋白复合物中;催化步骤2剪接体(同源物);细胞表面(同源物);与1,1,1-三氯-2-(邻氯苯基)-2-(对氯苯基)乙烷、17α-乙炔基雌二醇、2,3,7,8-四氯二苯并-对氧杂芑等物质相互作用。
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