Annotations for protein-coding gene sets of A. caninum and N. americanus.

We annotated predicted protein products with N-terminal signal sequences, conserved protein domains, orthologies to genes in related nematode species, and Gene Ontology (GO) terms describing biological and molecular functions. Protein-coding genes were predicted for A. caninum by Coghlan et al. [55] and for N. americanus by Logan et al. [44]. Since the annotation methods we used for these proteomes were identical to those we used for our A. ceylanicum v2.1 proteome, almost all the data columns used here are equivalent to those in S1 Table. Two data columns unique to these tables are Acan_ES and Necator_ES, which respectively denote A. caninum or N. americanus genes previously demonstrated by Morante et al. [45] or Logan et al. [44] to encode ES proteins. (XLSX)