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Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... Authors: Tzarum, N, Wilson, I.A, Law, M. Deposit date: 2020-04-25 Release date: 2020-08-19 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.667 Å) Cite: An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020

结合中和抗体(neutralizing antibody)HC1AM与非中和抗体(non-neutralizing antibody)E1的1a基因型丙型肝炎病毒(Hepatitis C Virus, HCV)包膜糖蛋白E2核心结构 描述符:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、包膜糖蛋白E2(Envelope glycoprotein E2)等 作者:Tzarum N、Wilson I.A、Law M 沉积日期:2020-04-25 发布日期:2020-08-19 最后修改日期:2024-10-30 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率3.667埃(Å) 引用文献:《HCV E2包膜蛋白中和表位的一种构象变体作为附加疫苗靶点》,Science Advances(Sci Adv),6卷,2020年
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2020-04-25
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