B-cell lymphoma, NOS - Unknown, 76 - Tissue image [3280730025609111]

This is the histopathological image of NASAL CAVITY AND MIDDLE EAR tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 76Clinical description: Right nasal cavity.Gender: UnknownDiagnosis:Classification: ICD-O_3.2Classification code: MALIGNANT LYMPHOMAS NOS OR DIFFUSEDiagnosis: B-cell lymphoma, NOSResult of the histopathological examination: Diffuse large B-cell lymphoma (DLBCL). IHC: :CD45(+), CD20(+), Bcl-6(+, MUM1(+), Bcl-2(+), c-myc (+, CD10(-), Ki-67 90%, CD3-, CD4-, CD5-, CD8- i CD43 -.Sample:Material: FFPECollecting method: Surgical biopsyTopography: RESPIRATORY SYSTEM AND INTRATORACIC ORGANSOrgan: NASAL CAVITY AND MIDDLE EARTissue: Nasal cavityType of staining: positive/IHCStaining: Not applicableAntibody: Melan ATechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存档于ZMDL-GUMED的鼻腔与中耳组织样本的组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪（放大倍数20倍）采集，并以DICOM格式存储。

以下为患者、样本及诊断的详细信息：
1. 患者信息：年龄76岁，临床表征为右侧鼻腔病变，性别未知。
2. 诊断信息：分类依据为ICD-O_3.2标准，分类编码为"未特指恶性淋巴瘤或弥漫性恶性淋巴瘤（MALIGNANT LYMPHOMAS NOS OR DIFFUSE）"；具体诊断为非特指B细胞淋巴瘤（B-cell lymphoma, NOS）；组织病理学检查结果为弥漫性大B细胞淋巴瘤（Diffuse large B-cell lymphoma, DLBCL）。免疫组化（IHC）结果如下：CD45(+)、CD20(+)、Bcl-6(+)、MUM1(+)、Bcl-2(+)、c-myc(+)，CD10(-)、Ki-67增殖指数90%，CD3-、CD4-、CD5-、CD8-、CD43-。
3. 样本信息：
- 样本材质：福尔马林固定石蜡包埋（FFPE）样本
- 采集方式：外科活检
- 解剖部位：呼吸系统及胸腔内器官（RESPIRATORY SYSTEM AND INTRATORACIC ORGANS），涉及器官为鼻腔与中耳，组织类型为鼻腔组织
- 染色类型：阳性染色/免疫组化染色（positive/IHC），未指定具体染色方案，所用抗体为Melan A
- 成像参数：采用Pannoramic 250 3DHistech设备采集，镜头放大倍数为20x
4. 机构来源：格但斯克医科大学