NEI Refractive Error Collaboration (AREDS). Homo sapiens

A genome-wide association study of refractive error using the Illumina 2.5M chip was performed using a subset of the control group from the original AREDS study. These control individuals are all Caucasian, do not have age-related macular degeneration (AMD) and were further screened to also exclude individuals with cataracts, retinitis pigmentosa, color blindness, other congenital eye problems, LASIK, artificial lenses, and other eye surgery. Refractive error at baseline enrollment into the AREDS study will be analyzed. Refractive error at baseline measured as spherical equivalent, plus baseline measures of axis, sphere and cylinder are available for each eye. Age, summary measures of education, and gender are also included as covariates. The individuals in this substudy can be linked... (for more see dbGaP study page.)