LecB from PA01 in complex with synthetic beta - fucosylamide

LecB from PA01 in complex with synthetic beta - fucosylamide Descriptor: 5-[3-(aminomethyl)phenyl]-~{N}-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]furan-2-carboxamide, CALCIUM ION, Fucose-binding lectin PA-IIL, ... Authors: Antonini, G, Varrot, A. Deposit date: 2024-07-12 Release date: 2025-04-16 Last modified: 2025-05-21 Method: X-RAY DIFFRACTION (1.739 Å) Cite: Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa - Burkholderia cenocepacia Infections: A Biophysical Study. J.Med.Chem., 68, 2025PA01来源的LecB与合成β-岩藻糖酰胺（beta-fucosylamide）形成的复合物，其配体描述为：5-[3-(氨甲基)苯基]-N-[(2S,3S,4R,5S,6S)-6-甲基-3,4,5-三(羟基)四氢吡喃-2-基]呋喃-2-甲酰胺，体系包含钙离子（CALCIUM ION）与岩藻糖结合凝集素PA-IIL（Fucose-binding lectin PA-IIL）等。作者：安东尼（Antonini, G）、瓦罗（Varrot, A）。入库日期：2024-07-12；发布日期：2025-04-16；最后修改日期：2025-05-21。检测方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.739埃）。引用文献：《针对两种细菌凝集素的双靶点糖模拟物对抗铜绿假单胞菌-洋葱伯克霍尔德菌感染：一项生物物理研究》，《药物化学杂志》（J.Med.Chem.），第68卷，2025年