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Biomimetic Total Synthesis of (+)-Chabranol

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Biomimetic_Total_Synthesis_of_Chabranol/2744908
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资源简介:
A concise, biomimetic total synthesis of the unprecedented terpenoid skeleton (+)-chabraol has been accomplished via 6 steps from the chiral epoxide 7, involving an intramolecular Prins double cyclization to yield the bicyclo[2.2.1] core of the natural product as the key step. The absolute configuration of natural chabranol was also designated through the first asymmetric total synthesis.
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2010-08-06
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