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Synthetic cystine addiction via programmed necrosis in VHL-deficient renal cell carcinoma

ChEBI2016-07-01 更新2026-07-12 收录

肾透明细胞癌代谢组学

肿瘤靶向治疗

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60422 数据链接链接失效反馈

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资源简介：

Synthetic cystine addiction via programmed necrosis in VHL-deficient renal cell carcinoma

应用场景：

创建时间：

2016-07-01

肿瘤靶向治疗

药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

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Uncoupling of PARP1 Trapping and Inhibition Using Selective PARP1 Degradation

PARP抑制剂机制

肿瘤靶向治疗

PARP1 inhibitors (PARPi) are known to kill tumor cells via two mechanisms (i.e., PARP1 catalytic inhibition vs. PARP1 trapping). The relative contribution of these two pathways in mediating the cytoto

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Regulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [HG-U133_Plus_2]

肿瘤靶向治疗

基因表达谱分析

U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ), when tumour is established in BALB/c SCID mice. At the e

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肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

江苏数据交易所80

Original images underlying Fig 3D.

肿瘤靶向治疗

RNA干扰

Expression of Concern: Specific Inhibition of Tumor Cells by Oncogenic EGFR Specific Silencing by RNA interference

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