Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine-3-hydroxyindazole inhibitor

Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine-3-hydroxyindazole inhibitor Descriptor: (7R)-7-methyl-2-[(3-oxo-2,3-dihydro-1H-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... Authors: Counago, R.M, dos Reis, C.V, Takarada, J.E, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) Deposit date: 2019-01-18 Release date: 2019-02-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine-3-hydroxyindazole inhibitor To Be Published

人痘苗相关激酶结合N,N-二丙炔基二氢蝶啶-3-羟基吲唑抑制剂的晶体结构
配体描述：(7R)-7-甲基-2-[(3-氧代-2,3-二氢-1H-吲唑-6-基)氨基]-5,8-二(丙-2-炔-1-基)-7,8-二氢蝶啶-6(5H)-酮、1,2-乙二醇、二(羟乙基)醚等
作者：Counago, R.M、dos Reis, C.V、Takarada, J.E、Azevedo, A、Guimaraes, C、Mascarello, A、Gama, F、Ferreira, M、Massirer, K.B、Arruda, P、Edwards, A.M、Elkins, J.M，结构基因组联盟（Structural Genomics Consortium, SGC）
提交日期：2019-01-18
发布日期：2019-02-20
最后修改日期：2023-10-11
实验方法：X射线衍射（2.2 Å）
引用说明：《人痘苗相关激酶结合N,N-二丙炔基二氢蝶啶-3-羟基吲唑抑制剂的晶体结构》，待发表