five

human VPS13C structure predicted by AlphaFold

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NIAID Data Ecosystem2026-03-13 收录
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https://zenodo.org/record/6803511
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Full-length human VPS13C isoform 1 comprises 3753 amino acids (a.a.). is predicted with AlphaFold2. Such structure is represented by a 29.3 nm long rod whose backbone is a narrow twisted β-sheet running along its entire length. The β-sheet forms the floor of a hydrophobic groove that extends throughout the rod and thus could mediate the sliding of lipids from one end to the other end of the protein.
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2022-07-07
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