Timp2
收藏rgd.mcw.edu2025-03-24 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=61312
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ENCODES a protein that exhibits integrin binding; metalloendopeptidase inhibitor activity; enzyme activator activity (ortholog); INVOLVED IN negative regulation of cell population proliferation; negative regulation of mitotic cell cycle; negative regulation of proteolysis; ASSOCIATED WITH Acute Lung Injury; Brain Injuries; cardiomyopathy; FOUND IN cell surface; extracellular space; growth cone; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-nicotine
编码一种表现整合素结合、金属肽酶抑制剂活性以及酶激活活性(同源酶)的蛋白质;参与细胞增殖负调控、有丝分裂细胞周期负调控、蛋白质降解负调控;与急性肺损伤、脑损伤、心肌病相关;存在于细胞表面、细胞外空间、生长锥中;与(+)毛果芸香碱、(R)-去甲肾上腺素、(S)-尼古丁相互作用。
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