Rh(III)-Catalyzed Double C–H Functionalization of Indoles with Cyclopropenones via Sequential C–H/C–C/C–H Bond Activation

An unprecedented Rh(III)-catalyzed double C–H functionalization of indoles with cyclopropenones via sequential C–H/C–C/C–H bond activation has been developed. This procedure represents the first example for assembling of cyclopenta[b]indoles utilizing cyclopropenones as 3C synthons. This powerful approach shows excellent chemo- and regioselectivity, wide functional group tolerance, and good reaction yields.