George E. Palade (University of California, San Diego) (2011) CIL:7603, Rattus rattus, hepatocyte. CIL. Dataset

Morphology of the endoplasmic reticulum during a period of rapid cell differentiation. This micrograph shows two typical patterns of rough endoplasmic reticulum (RER) in developing liver from a one day old rat. Some RER is arranged in arrays of parallel flat cisternae (shown here in cross-section) and other RER (cisternae and/or tubules) encircles the mitochondria (Mt). The RER is defined by the presence of bound ribosomes (RiB). Many free ribosomes (RiF) are also seen in the cytoplasm between the parallel arrays of RER.

Identical labeled image available as CIL# 7605. Similar to micrographs published in Dallner G, Siekevitz P, Palade GE. J Cell Biol. 1966;30:73-96. Original image is in the Palade Collection, University of California, San Diego.

本研究呈现了细胞快速分化期间内质网的形态学变化。该显微照片展示了来自一天龄大鼠发育中的肝脏中两种典型的粗面内质网（RER）模式。部分RER排列成平行扁平的囊泡阵列（此处为横截面所示），而其他RER（囊泡和/或管状结构）环绕着线粒体（Mt）。内质网的特征在于其表面附着有结合的核糖体（RiB）。在RER平行阵列之间的细胞质中，还可见到许多游离的核糖体（RiF）。可获取与Dallner G, Siekevitz P, Palade GE在《细胞生物学杂志》1966年第30期发表的显微照片相似的标记图像，CIL编号为7605。原始图像收藏于加州大学圣地亚哥分校的Palade藏品中。