Protecting Group-Free Total Synthesis of (−)-Lannotinidine B
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://figshare.com/articles/dataset/Protecting_Group_Free_Total_Synthesis_of_Lannotinidine_B/2501125
下载链接
链接失效反馈官方服务：
资源简介：
The first total synthesis of (−)-lannotinidine
B, a unique
tetracyclic constitutent of Lycopodium annotinum,
has been accomplished in 10 steps with 23% overall yield. The completed
short and efficient synthesis is characterized with three highly chemo-
and/or stereoselective reductive-amination steps to furnish the desired trans-fused 6/6 bicycle and the aza seven-membered ring
system, and a direct intramolecular acyloin condensation to deliver
the cyclopentanone moiety, as well as successful application of a
protecting group-free strategy and an optimal redox order.
创建时间：
2016-02-20
