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Deregulation of the endogenous C/EBPM-NM-2 LIP isoform predisposes to tumorigenesis

ChEBI2014-12-16 更新2026-07-21 收录

肿瘤发生机制

蛋白质异构体

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53770 数据链接链接失效反馈

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资源简介：

Deregulation of the endogenous C/EBPM-NM-2 LIP isoform predisposes to tumorigenesis

应用场景：

创建时间：

2014-12-16

肿瘤发生机制

细胞衰老调控

Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit

NIAID Data Ecosystem110

Perspectives on This Article from Nicotine Does Not Enhance Tumorigenesis in Mutant K - Ras –Driven Mouse Models of Lung Cancer

小鼠癌症模型

肿瘤发生机制

Perspectives on This Article from Nicotine Does Not Enhance Tumorigenesis in Mutant K-Ras–Driven Mouse Models of Lung Cancer

NIAID Data Ecosystem60

YAP1 and PRDM14 converge to regulate cell survival and tumorigenesis

肿瘤发生机制

疾病靶点发现

The transcriptional co-activator YAP1 oncogene is the downstream effector of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration and tumorigenesis. Multiple cancers are dep

NIAID Data Ecosystem50

NGS-mRNA in lung tissues in RAG1-/- and in RAG1-/- Sgo1-/+ mice

基因表达分析

肿瘤发生机制

We compared lung mRNA expression profiles between RAG1-/- control and RAG1-/- Sgo1-/+ chromosome instability model mice. RAG1-/-Sgo1-/+ mice developed significantly more spontaneous lung tumors. Char

NIAID Data Ecosystem80

p53 amyloid formation induced cellular transformation and tumor formation in xenograft model

p53

肿瘤发生机制

p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.

NIAID Data Ecosystem50

Deregulation of the endogenous C/EBPM-NM-2 LIP isoform predisposes to tumorigenesis

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