Thermodynamic procedure to synthesize heteropolymers that can renature to recognize a given target molecule.
收藏PubMed Central1994-12-20 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC45563/
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资源简介：
We suggest a procedure to synthesize polymers with characteristics similar to those observed in globular proteins: renaturability and the existence of an "active site" capable of specifically recognizing a given target molecule. This procedure is investigated by computer simulation, which finds a yield of up to 65%. We believe that, in principle, this scheme can be realized in vitro. The applicability of this approach as a model of prebiotic synthesis in vivo is also discussed. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1994-12-20
